Physical Pharmaceutics 1 Notes PDF Free

Hello dear readers, in this post, I’ve provided an overview as well as download links to notes from Physical Pharmaceutics 1 (BP302T) according to the PCI syllabus for B Pharm 3rd Semester 2023.


In the notes in Physical Pharmaceutics 1, we have provided two kinds of notes, namely Handwritten notes, and Standard notes.

Physical Pharmaceutics 1 notes deal with the diverse physical and physicochemical properties and the underlying principles of dosage forms and formulations. The theory and the practical aspects of the course help students gain a greater understanding of the various aspects of formulation development research and stability and stability studies of pharmaceutical dosage forms.

Friends In the Physical Pharmaceutics 1 as per the syllabus copy of PCI B Pharm 3rd semester, there are a total of 5 units in this subject.

Read this: B Pharma third Semester all Study Material PDF Free

Download Physical Pharmaceutics 1 All Units Notes PDFs FREE

Click on the following download buttons below the names of the units to download Physical Pharmaceutics 1 both Handwritten and Standard Notes.

In the Physical Pharmaceutics 1 Notes Pdfs, the following chapters are explained in detail.


Drugs’ solubility – expressions of solubility, mechanisms of interactions between solute and solvent Ideal parameters for solubility, Solvation, and Association, a quantitative study of the elements that affect the solubility of drugs diffusion mechanisms of a biological system. Solubility of gas in liquids the solubility and permeability of liquids in liquids (Binary solutions Ideal solutions) Raoult’s law, actual solutions. Critical Solution Temperature, partially miscible liquids, and their applications. Law of distribution, the limitations, and their applications


States of matter and the properties of Matter – State of Matter and modifications in matter’s state, heat-latent sublimation critical point, eutectic mixed gas, aerosols, and inhalers liquid crystals, liquid complexes and glassy states, solid crystals, amorphous and polymorphism.

Physical characteristics of drug molecules – Refractive index, optical rotation, and dielectric constant dissociation and dipole moments determinations, and their applications


Interfacial and surface phenomenon – Liquid interface, surface, and interfacial tensions, surface free energy measurement of surface and interfacial tensions. Spreading coefficient, adsorption at interfaces between liquids Surface-active substances, the HLB Scale detergency, solubilization, Adsorption at the solid interfaces.


Complexation and binding to proteins – Introduction and classification of Complexation, Applications, methods for study, analysis of protein binding complexation and drug action crystal structures of complexes, and the thermodynamic treatment of stability constants.


pH, buffers, as well as Isotonic solutions – Sorensen’s pH scale measurement of pH (electrometric as well as calorimetric) applications of buffers. equations, buffer capacity buffers in pharmaceutical and biological processes and buffered Isotonic solutions.

If you’re satisfied with the Physical Pharmaceutics 1 notes, make sure to leave your comments in the comment section.

2 thoughts on “Physical Pharmaceutics 1 Notes PDF Free”

Leave a Comment