Pharmacology 1 Notes PDF Free

Hello dear readers, in this post, I’ve provided the overview and download links to notes from Pharmacology 1 (BP404T) according to the PCI syllabus for B Pharm 4th Semester 2023.


Notes from Pharmacology 1 we have listed two kinds of notes: Handwritten notes and Standard notes.

The primary goal for Pharmacology 1 notes is to understand the effects of drugs on living creatures and to understand how they can be used to improve therapeutic methods. The subject provides information regarding the drug’s mechanisms of action, biochemical and physiological effects (pharmacodynamics) and also metabolism, absorption, distribution, and elimination (pharmacokinetics) as well as negative effects as well as clinical applications dosages, interactions, contraindications, as well as the routes of administration of various types of drugs.

Friends Pharmacology 1 is the subject of the 4th semester of the B Pharm course, and as per the syllabus copy of PCI B Pharm 4th semester, there are a total of 5 units in this subject.

Read this: B Pharma 4th Semester all Study Material PDF Free

Download Pharmacology 1 All Units Notes PDFs FREE

Click on the following download buttons below the names of the units to download Pharmacology 1 both Handwritten and Standard Notes.

In the Pharmacology 1 Notes Pdfs, the following chapters are explained in detail.


1. General Pharmacology

A. Introduction to Pharmacology – Definition of historic landmarks, the scope of pharmacology and the source of drugs, fundamental drugs concepts and methods of administration, antagonists, Agonists (competition and non-competitive) and spare receptors, dependence, tolerance, addiction, and tachyphylaxis. Also, idiosyncrasy allergies.

B. Pharmacokinetics- Membrane transportation absorption, distribution, metabolism, and elimination of drugs. Enzyme induction, inhibition of enzymes elimination kinetics


A. Pharmacodynamics – Principles, and mechanisms of the action of drugs. Theories of the receptor and classification of their receptors control of receptors. Drug receptors interactions and signals transduction mechanisms, G protein-coupled receptors Ion channel receptor transmembrane enzyme-linked receptors. JAK-STAT binding molecule and receptors regulate transcription factors’ therapeutic index, effects of drugs, as well as factors that alter the action of drugs.

B. adverse drug reactions.

C. Interactions between drugs (pharmacokinetic and pharmacodynamic)

D. Discovery and clinical evaluation of novel drug discovery phases – Drug discovery phase preclinical evaluation phase and clinical trial phase and phases of clinical trials and Pharmacovigilance.


2. Pharmacology of the drugs that affect your peripheral nervous system.

A. The organization and function of ANS.

Neurohumoral transmission-transmission, and classification of neurotransmitters.

C. Parasympathomimetic, Parasympatholytic, Sympathomimetics, sympatholytic.

D. Blockers of neuromuscular activity as well as skeletal muscle relaxation agents (peripheral).

E. local anesthetic agents. F. Treatments for myasthenia gravis and the glaucoma


3. The effects of pharmaceuticals on the Central nervous system.

A. Neurohumoral transmission within the C.N.S. special emphasizes the importance of different neurotransmitters, such as GABA, Glutamate, Glycine, serotonin, and dopamine.

B. Pre-anesthetic as well as general anesthetics.

C. Sedatives, hypnotics, and centrally acting muscle relaxants.

D. Anti-epileptics.

E. Disulfiram and alcohols.


3. Pharmacology of drugs acting on the central nervous system

A. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents, anti-manic, and hallucinogens.

B. Treatments for Parkinson’s dementia and Alzheimer’s.

C. CNS stimulants and nootropics.

D. Opioid antagonists and analgesics and antagonists.

E. Addiction to drugs as well as drug addiction tolerance, dependence, and addiction.

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