In this post, I have shared an overview and download links of Pharmacological Screening Methods or Experimental Pharmacology (BP810ET) Notes PDF according to the PCI syllabus for B Pharmacy 8th Semester.
In the notes on Pharmacological Screening Methods, I have given two types of notes, namely Handwritten notes, and Standard notes.
Pharmacological Screening Methods notes are designed to impart the basic knowledge of preclinical studies in experimental animals including design, conduct, and interpretations of results.
Pharmacological Screening Methods is an Elective Theory subject of the 8th semester of the B Pharmacy course, there is a total of 5 units in this subject.
Download Pharmacological Screening Methods All Units Notes PDFs FREE
Click on the following download buttons below the names of the units to download Pharmacological Screening Methods both Handwritten and Standard Notes.
In the Pharmacological Screening Methods Notes PDFs, the following chapters are explained in detail.
Laboratory Animals: Study of CPCSEA and OECD guidelines for maintenance, breeding and conduct of experiments on laboratory animals, Common lab animals: Description and applications of different species and strains of animals. Popular transgenic and mutant animals. Techniques for collection of blood and common routes of drug administration in laboratory animals, Techniques of blood collection and euthanasia.
Preclinical screening models:
a. Introduction: Dose selection, calculation and conversions,
preparation of drug solution/suspensions, grouping of animals and
importance of sham negative and positive control groups.
Rationale for selection of animal species and sex for the study.
b. Study of screening animal models for
Diuretics, nootropics, anti-Parkinson’s,antiasthmatics,
Preclinical screening models: for CNS activity- analgesic,
antipyretic,anti-inflammatory, general anaesthetics, sedative and
hypnotics, antipsychotic, antidepressant, antiepileptic, antiparkinsonism, alzheimer’s disease
Preclinical screening models: for ANS activity, sympathomimetics,
sympatholytics, parasympathomimetics, parasympatholytics, skeletal
muscle relaxants, drugs acting on eye, local anaethetics
Preclinical screening models: for CVS activity- antihypertensives,
diuretics, antiarrhythmic, antidyslepidemic, anti-aggregatory, coagulants, and anticoagulants
Preclinical screening models for other important drugs like antiulcer,
antidiabetic, anticancer and antiasthmatics.
Research methodology and Biostatistics:
Selection of research topic, review of literature, research hypothesis
and study design
Pre-clinical data analysis and interpretation using Students ‘t’ test.
and One-way ANOVA. Graphical representation of data.