Hello all! in this post I have shared an overview and download links of notes of Medicinal Chemistry 3 (BP601T) according to the PCI syllabus for B Pharm 6th Semester 2023.
Overview
In the notes of Medicinal Chemistry 3 (BP601T), we have given two types of notes namely Handwritten notes and Standard notes.
Medical Chemistry 3 notes are designed to give an understanding of the basics of chemistry which is the basis of the structure and the therapeutic benefits that come with drugs. The course will focus on the most recent techniques for the rational design of drugs like the quantitative structure-activity relation (QSAR) and the idea of a prodrug, which is a blend of chemistry and Computer-aided Drug Design (CADD). The subject is also focused on chemical chemistry and the mechanism of action metabolic processes and the adverse reaction that occurs in structures-activity relationships (SAR) for medical and therapeutic applications, as well as making vital drugs.
Read this: B Pharma 6th Semester all Study Material PDF Free
Friends Medicinal Chemistry 3 is the subject of the 6th semester of the B Pharm course, and as per the syllabus copy of PCI B Pharm 6th semester, there are a total of 5 units in this subject.
Download Medicinal Chemistry 3 All Units Notes PDFs FREE
Click on the following download buttons below the names of the units to download Medicinal Chemistry 3 both Handwritten and Standard Notes.
In the Medicinal Chemistry 3 Notes Pdfs, the following chapters are explained in detail.
UNIT-1
Antibiotics
Background History, nomenclature, & Stereochemistry classification of chemical degradation are among the most important products of this category.
B-Lactam antibiotics: Cephalosporins, Penicillin, b-Monobactams, Lactamase inhibitors
Aminoglycosides: Neomycin, Streptomycin, Kanamycin
Tetracyclines: Tetracycline, Oxytetracycline, Chlortetracycline, Minocycline, Doxycycline
UNIT-2
Antibiotics
Background History, nomenclature, & Stereochemistry. The connection between structure & activity degradation classification, as well as the most significant product from these categories.
Macrolide: Clarithromycin, Erythromycin, Azithromycin.
Miscellaneous: Clindamycin, Chloramphenicol.
Prodrugs: Fundamental concepts & applications of design for the prodrugs.
Malaria-fighting medications: & the root causes of Malaria.
Quinolines: SAR, Chloroquine, Quinine sulfate, Amodiaquine, Primaquine phosphate, Pamaquine, Quinacrine hydrochloride, and Mefloquine.
Biguanides & dihydro triazines: Proguanil, Cycloguanil pamoate.
Miscellaneous: Artesunate, Pyrimethamine, Artemether, Atovaquone.
UNIT-3
Anti-tubercular Agents
Synthetic antitubercular agents: Ethionamide, Isoniazid, Ethambutol, Pyrazinamide, Para aminosalicylic acid.
Anti-tubercular antibiotics: Rifabutin, Rifampicin, Cyclomerize Streptomycin, Capreomycin sulfate.
Anti-infective medicines for urinary tract infection
Quinolones: SAR quinolones, Norfloxacin, Nalidixic Acid, Enoxacin, Ciprofloxacin, Ofloxacin, Lomefloxacin, Sparfloxacin, Gemifloxacin, Moxifloxacin
Miscellaneous: Nitrofurantoin, Furazolidone, Methenamine.
Antiviral agents: Rimantadine hydrochloride, Amantadine hydrochloride, Idoxuridine trifluoride, Acyclovir, Ganciclovir, Zidovudine, Didanosine, Zalcitabine, Lamivudine, Loviride, Delavirdine, Ribavirin, Saquinavir, Indinavir, Ritonavir.
UNIT-4
Antifungal agents:
Antifungal antibiotics: Nystatin, Amphotericin-B, Natamycin, Griseofulvin.
Synthetic Antifungal agents: Econazole, Clotrimazole, Butoconazole, Oxiconazole Tioconazole, Miconazole, Ketoconazole, Terconazole, Itraconazole, Fluconazole, Naftifine hydrochloride, Tolnaftate.
Anti-protozoal Agents: Tinidazole, Metronidazole, Ornidazole, Diloxanide, Iodoquinol, Pentamidine Isethionate, Atovaquone, Eflornithine.
Anthelmintics: Thiabendazole, Diethylcarbamazine citrate, Mebendazole, Albendazole, Nicolaides, Oxamniquine, Praziquantel, Ivermectin.
Sulphonamides & Sulfones
The development of chemical compounds as well as classification of the development of historical as well as SAR Sulfonamides: Sulphathiazole, Sulfisoxazole, Sulphathiazole, Sulfacetamide, Sulphapyridine, Sulfamethoxazole, Sulphadiazine, Mafenide acetate, Sulfasalazine.
Folate reductase inhibitors: Cotrimoxazole, Trimethoprim.
Sulfones: Dapsone.
UNIT-5
The Beginning of Drug Design
It is possible to use many techniques employed in making substances.
Physical parameters are utilized as a part of qualitative relationships between structures & activities (QSAR) like the electronic partition coefficient Hammet’s parameter, the Taft Steric parameter, & Hansch studies. Pharmacophore model & docking methods.
Combinatorial Chemistry: Concept & applications within the field of chemical chemistry. This covers the solid phase, as well as the formation of solutions within the phases.
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